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Procyanidin B1

CAS No.:20315-25-7

Procyanidin B1
Catalogue No.: BP1146
Formula: C30H26O12
Mol Weight: 578.526
Botanical Source: Grape Seed
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Product name: Procyanidin B1
Synonym name: Proanthocyanidin B1
Catalogue No.: BP1146
Cas No.: 20315-25-7
Formula: C30H26O12
Mol Weight: 578.526
Botanical Source: Present in red wine
Physical Description: Powder
Type of Compound: Procyanidins

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.

Descriptions:
Procyanidin B1, one of the major components of Flavangenol, also suppresses fat accumulation and induced mRNA expression of the fatty acid oxidative enzymes.[1]
Procyanidin B1 suppresses HCV RNA synthesis, possibly as a HCV RNA polymerase inhibitor, it might contribute towards the development of more effective inhibitors for HCV infection from natural plants.[2]
Procyanidin B1 has neuroprotective effects, may attenuate the activation of caspase-3 by inhibiting that of caspase-8 and -9. [3]
Procyanidin B1 has anti-inflammatory effect on LPS-treated THP1 cells via interaction with the TLR4–MD-2 heterodimer and p38 MAPK and NF-κB signaling.[4]
Procyanidin B1 strongly inhibits the proliferation of HeLa S3 cells. [5]

References:
[1] Sano A, Yamakoshi J, Tokutake S, et al. Biosci Biotech Bioch, 2003, 67(5):1140-3.
[2] Li S, Kodama E N, Inoue Y, et al. Antiviral Chem Chemoth, 2010, 20(6):239-48.
[3] Kanno H, Kawakami Z, Tabuchi M, et al. J Ethnopharmacol, 2014, 159:122–8.
[4] Jing Xing, Rui Li, Nan Li,et al. Mol Cell Biochem, 2015, 407(1-2):89-95.
[5]Okamoto S, Ishihara S, Okamoto T, et al. Molecules, 2014, 19(2):1775-85.
[6] Zhao C Y, Wang M, Zhang G W, et al. J Shenyang Pharm Univ, 2014, 31(1):32-5.