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METHOD FOR MASS PRODUCTION OF GINSENOSIDE RH2-MIX

Journal name: Free Patents Online
Literature No.:
Literature Url: http://www.freepatentsonline.com/y2019/0112629.html
Date publication:04/18/2019
Abstact

The present invention relates to a method for mass production of ginsenoside Rh2-Mix. The present invention includes treating PPD-Mix with an organic acid and heat to obtain Rg3-Mix and treating the obtained Rg3-Mix using a recombinant GRAS strain in the Rg3-Mix to produce Rh2-Mix, and thereby facilitates the mass production of ginsenoside Rh2-Mix using β-glucosidase, which has been known to be difficult. Further, the present invention is advantageous in that the Rh2-Mix can be produced in high yield even at high temperatures, and mass production thereof for industrial purposes is practical as the production process is simple and more economical than direct use of an enzyme.

… Nanjing Zelang Medical Technology Co., Ltd. (China), while ginsenosides
20(R)
Rh2 , Rk1 , Rg5 , Rk2 , and Rh3 were purchased from Chengdu Biopurify Phytochemicals Co., Ltd. (China). The PPD-Mix-type ginsenosides …