Synonym name:
Catalogue No.: BP0145
Cas No.: 33457-62-4
Formula: C₁₉H₁₈O
Mol Weight: 262.352
Botanical Source: Alnus pendula and Curcuma xanthorrhiza (Java turmeric)

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

For Reference Standard and R&D, Not for Human Use Directly.
Inquire for bulk scale.

Description:

Alnustone has anti-inflammatory, antihepatotoxic and antiemetic activities,

References:

Planta Med. 1993 Oct;59(5):451-4.    

Three non-phenolic diarylheptanoids with anti-inflammatory activity from Curcuma xanthorrhiza.   

METHODS AND RESULTS:

Bioassay-guided fractionation of a hexane extract of the rhizomes of Curcuma xanthorrhiza Roxb. (Zingiberaceae) led to the isolation of three non-phenolic diarylheptanoids, identified mainly by high-field 1H-NMR as trans-trans-1,7-diphenyl-1,3-heptadien-4-one (Alnustone), trans-1,7-diphenyl-1-hepten-5-ol, and trans,trans-1,7-diphenyl-1,3-heptadien-5-ol. The latter is reported for the first time as a plant constituent. Germacrone, curzerenone, and cinnamaldehyde were also isolated and identified. 

CONCLUSIONS:

The three diarylheptanoids all exerted significant anti-inflammatory activity in the assay of carrageenin-induced hind paw edema in rats.   

HPLC of Alnustone