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Icariside I

CAS No.:56725-99-6

Icariside I
Catalogue No.: BP0758
Formula: C27H30O11
Mol Weight: 530.526
Botanical Source: Epimedii folium
Contacts
+86-28-82633860  +86-18080483897
 
Email: sales@biopurify.com biopurify@gmail.com

Icariside I

CAS No.:56725-99-6

Icariside I
Catalogue No.: BP0758
Formula: C27H30O11
Mol Weight: 530.526
Botanical Source: Epimedii folium
Contacts
+86-28-82633860  +86-18080483897
 
Email: sales@biopurify.com biopurify@gmail.com
Over 15 years of industry experience in phytochemicals from R&D(reference substances) to Industrialization, please feel free to contact us!

Synonym name:
Catalogue No.: BP0758
Cas No.: 56725-99-6
Formula: C27H30O11
Mol Weight: 530.526
Botanical Source: Epimedium grandiflorum and Epimedium macranthum

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

For Reference Standard and R&D, Not for Human Use Directly.
Inquire for bulk scale.

 

 

 

Description:

Icariside I is a metabolite product of Icariin.

 

References:

J Cell Physiol. 2013 Mar;228(3):513-21.    

Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling.  

METHODS AND RESULTS:

Icariin, a prenylated flavonol glycoside isolated from Epimedium herb, stimulates osteogenic differentiation of BMSCs and inhibits bone resorption activity of osteoclasts. Icariin, whose metabolites include Icariside I, Icariside II, icaritin, and desmethylicaritin, has no estrogenic activity. However, icariin is more potent than genistein in promoting osteogenic differentiation and maturation of osteoblasts. The existence of a prenyl group on C-8 of icariin molecular structure has been suggested to be the reason why icariin is more potent than genistein in osteogenic activity. 

CONCLUSIONS:

Thus, the prenylflavonoids may represent a class of flavonoids with a higher osteogenic activity.