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6-alpha-Hydroxygeniposide

CAS No.:52613-28-2

6-alpha-Hydroxygeniposide
Catalogue No.: BP1667
Formula: C17H24O11
Mol Weight: 404.368
Botanical Source: Hedyotis Diffusae Herba
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Product name: 6-alpha-Hydroxygeniposide
Synonym name: 6-Epiferetoside
Catalogue No.: BP1667
Cas No.: 52613-28-2
Formula: C17H24O11
Mol Weight: 404.368
Botanical Source: "Gardenia jasminoides, Plantago lagopus and Mussaenda pubescens. Component of Zhi Zi"
Physical Description: Powder
Type of Compound: Iridoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.


 

Description:

Ddeacetylasperulosidic acid methyl ester can lower the blood glucose level in normal mice.

 

References:

Biol Pharm Bull. 1996 Jan;19(1):160-1.    

Four iridoidal glycosides, deacetylasperulosidic acid methyl ester (DE), scandoside methyl ester (SC), geniposide (GE) and gardenoside (GA) isolated from Gardenia jasminoides Ellis grandiflora Makino leaves, were tested hypoglycemic activity in mice. DE l    

METHODS AND RESULTS:

Four iridoidal glycosides, Deacetylasperulosidic acid methyl ester (DE), scandoside methyl ester (SC), geniposide (GE) and gardenoside (GA) isolated from Gardenia jasminoides Ellis grandiflora Makino leaves, were tested hypoglycemic activity in mice. DE lowered the blood glucose level in normal mice. 

CONCLUSIONS:

However, SC, GE and GA did not affect the blood glucose level in normal mice, indicating that the absolute configuration of 6 position hydroxy based (OH) should be essential for the biological activity.