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CAS No.:14260-99-2

Catalogue No.: BP1666
Formula: C19H26O12
Mol Weight: 446.405
Botanical Source: Hedyotis Diffusae Herba
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Product name: Daphylloside
Synonym name: Methyl asperulosidic acid
Catalogue No.: BP1666
Cas No.: 14260-99-2
Formula: C19H26O12
Mol Weight: 446.405
Botanical Source: "Daphniphyllum macropodum; Gardenia jasminoides, Plantago lagopus and Mussaenda pubescens. Component of Zhi Zi"
Physical Description: Powder
Type of Compound: Iridoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.



Daphylloside, and asperuloside can be suggested as endoplasmic reticulum stress regulators.



Vietnam Journal of Chemistry, 2015, 53(2e).    

Iridoid glycosides from Morinda tomentosa and their endoplasmic reticulum stress modulation activity  

Three iridoids 1 - 3, asperulosidic acid, Daphylloside, and asperuloside, were isolated from the methanol extract of the leaves of Morinda tomentosa. 


Their chemical structures were elucidated by 1D- and 2D-NMR spectra and in comparison with those reported in the literature. The effects of these compounds on the endoplasmic reticulum stress in XBP1-eGFP-transfected the 293 T cells were measured. Compound 3 significantly reduced the ER-stress both in DMSO-treated and thapsigargin-treated cells. Unlike this compound, compound 3 selectively reduced thapsigargin-induced ER-stress without any effect on the level of XBP1 splicing in DMSO-treated cells. 


These results suggested that compounds 2 and 3 can be suggested as new ER stress regulators.