Product name: Genistin
Synonym name: Genistein 7-glucoside; Genistoside
Catalogue No.: BP0635
Cas No.: 529-59-9
Formula: C21H20O10
Mol Weight: 432.381
Botanical Source: Genista spp., Lupinus spp. and a number of other spp. in the Leguminosae subfamily Papilionoideae. Also in wood of Prunus aequinoctalis, Prunus avium and Prunus nipponica
Physical Description: Powder
Type of Compound: Flavonoids
Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.
Descriptions:
Genistin and daidzin are among the major isoflavonoids in soybeans and soy products,
genistin has antioxidant activity and anticarcinogenic properties, can inhibit UV light-induced plasmid DNA damage and cell growth in human melanoma cells.[1]
Genistein and genistin inhibit cell proliferation by disrupting the cell cycle, which is strongly associated with the arrest induction of either G1 or G2/M phase and may induce apoptosis, speculates that both genistein and genistin may prove useful as anticancer drugs and that the combination of genistein and genistin may have further anticancer activity.[2]
Dietary genistin can stimulate growth of estrogen-dependent breast cancer tumors similar to that observed with genistein.[3]
Genistin and daidzin have preventive effects on bone loss in ovariectomized rats fed a calcium-deficient diet.[4]
References:
[1] Russo A, Cardile V, Lombardo L, et al. J Nut Biochem, 2006, 17(2):103-8.
[2] Choi E J, Kim T, Lee M S. Life Sci, 2007, 80(15):1403-8.
[3] Allred C D, Ju Y H, Allred K F, et al. Carcinogenesis, 2001, 22(10):1667-73.
[4] Ishida H, Uesugi T, Hirai K, et al. Biol Pharml Bull, 1998, 21(1):62-6.
[5] Suo Z R, Qin H Y, Li-Cheng D U.Chinese J Pharm Anal, 2009,29(10):1662-4.
