Shikonin

Synonym name:
Cas number: 54952-43-1; 517-89-5
Formula: C16H16O5
Mol Weight: 288.295
Purity: >98% by HPLC
Botanical Source: Arnebia euchroma
Packing: On customer requirements, From milligrams to grams
Remark: In stock, customized for large scale

For Standard and R&D,Not for Human Use Directly
 

Shikonin is a naphthoquinone found in the Chinese herb Arnebia euchroma (Royle) Johnst and Arnebia guttata Bunge. It inhibits TNF-α- and B6 melanoma-induced angiogenesis in mice. It blocks expression of integrin αvβ3 and inhibits endothelial cell proliferation and migration in vitro.

References:

1, Shikonin, a component of chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1.       Antimicrob Agents Chemother. 2003 Sep;47(9):2810-6. 

2, Shikonin production by extractive cultivation in transformed-suspension and hairy root cultures of Lithospermum erythrorhizon 
Annals of the New York Academy of Sciences, Vol 745, Issue 1 442-454,1994 

3, Genetic Engineering on Shikonin Biosynthesis: Expression of the Bacterial ubiA Gene in Lithospermum erythrorhizon 
Plant and Cell Physiology, 2000, Vol. 41, No. 8 911-919

Starting at: $65.00